Yes - eventually
The first term was very tiring and quite stressful for all concerned, longer days, travelling to school, new people and experiences, minor illnesses due to being tired. Things settled down after Christmas and by Easter it felt like DC had been there for ever. DC is doing well academically, has made new friends in all year groups, has participated in sporting teams and has really matured since September. I can't believe that this time last year we were looking forward to induction days, buying uniform and new parents evenings!
So - don't expect an easy ride for the first few weeks or so. Tears, tantrums, have we done the right thing etc are all normal. Go with the flow - the good will very soon outweigh the bad. My experience has been that the school take every opportunity to praise, reward and encourage new Y7's and there is just the right balance of hand-holding without molly-coddling.
Of the 60+ children DC was at primary school with all but 1 have settled well at 5 different upper schools, 3 grammar schools and independent schools - I would say there are pretty good odds that your DC will settle well too